Tummy Tone features vegetarian, gluten- and dairy-free, patented HOWARU® Shape Bifidobacterium animalis subsp lactis B420. This probiotic strain has been proven safe, effective, and well tolerated. It has been shown to assist with healthy body composition by improving gut barrier function, supporting the reduction of body fat mass, and promoting less calorie consumption.
References
1. Singh VP, Sharma J, Babu S, et al. Role of probiotics in health and disease: a review. J Pak Med Assoc. 2013 Feb;63(2):253-7. [PMID: 23894906]
2. Report of a Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics in Food. FAO; London, ON, Canada. 30 April–1 May 2002. https://www. who.int/foodsafety/fs_management/en/probiotic_guidelines.pdf. Accessed December 11, 2018.
3. Wilkins T, Sequoia J. Probiotics for gastrointestinal conditions: a summary of the evidence. Am Fam Physician. 2017 Aug 1;96(3):170-178. [PMID: 28762696]
4. Markowiak P, Śliżewska K. Effects of probiotics, prebiotics, and synbiotics on human health. Nutrients. 2017 Sep 15;9(9). pii: E1021. [PMID: 28914794]
5. Sanders M, Merenstein C, Merrifield C, et al. Probiotics for human use. Nutrition Bulletin. 2018 Sept;43(3):212–225. doi: 10.1111/nbu.12334. https://onlinelibrary. wiley.com/doi/epdf/10.1111/nbu.12334. Accessed December 11, 2018.
6. Kadooka Y, Sato M, Imaizumi K, et al. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. Eur J Clin Nutr. 2010 Jun;64(6):636-43. [PMID: 20216555]
7. Stenman LK, Lehtinen MJ, Meland N, et al. Probiotic with or without fiber controls body fat mass, associated with serum zonulin, in overweight and obese adultsrandomized controlled trial. EBioMedicine. 2016 Nov;13:190-200. [PMID: 27810310]
8. Putaala H, Salusjärvi T, Nordström M, et al. Effect of four probiotic strains and Escherichia coli O157:H7 on tight junction integrity and cyclo-oxygenase expression. Res Microbiol. 2008 Nov-Dec;159(9-10):692-8. [PMID: 18783733]
9. Stenman LK, Waget A, Garret C, et al. Potential probiotic Bifidobacterium animalis ssp. lactis 420 prevents weight gain and glucose intolerance in diet-induced obese mice. Benef Microbes. 2014 Dec;5(4):437-45. [PMID: 25062610]
10. Hibberd AA, Yde CC, Ziegler ML, et al. Probiotic or synbiotic alters the gut microbiota and metabolism in a randomised controlled trial of weight management in overweight adults. Benef Microbes. 2018 Dec 10:1-16. [PMID: 30525950]
